CAS No.
[134612-80-9(Unlabeled)]
Therapeutic Uses
Anti-Parkinsons
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
3-O-Methyl Tolcapone-d4, 134612-80-9(Unlabeled)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
3-O-Methyl Tolcapone-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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3-O-Methyl Tolcapone-d4 usage and description
3-O-Methyl Tolcapone D4 is a stable isotope-labeled analog of 3-O-Methyl Tolcapone, which is a potent and selective inhibitor of catechol-O-methyltransferase (COMT). The chemical formula of 3-O-Methyl Tolcapone D4 is C15H8D4NO5, and its molecular weight is 300.35 g/mol.
COMT is an enzyme that is involved in the metabolism of dopamine, norepinephrine, and epinephrine. By inhibiting the activity of COMT, 3-O-Methyl Tolcapone D4 increases the bioavailability of these neurotransmitters in the brain, which can lead to improved cognitive function and reduced symptoms of Parkinson's disease.
3-O-Methyl Tolcapone D4 is primarily used as a research tool in pharmacological studies that aim to understand the mechanism of action of COMT inhibitors and their potential therapeutic applications. This stable isotope-labeled analog can be used in kinetic studies, metabolic profiling, and pharmacokinetic analysis to track the fate of the drug in biological systems.
In summary, 3-O-Methyl Tolcapone D4 is a specialized chemical compound that has potential applications in the field of neuroscience research. It can be utilized to investigate the role of COMT in the metabolism of neurotransmitters and to evaluate the pharmacological properties of COMT inhibitors.