Product Detail
3-Hydroxy Bortezomib-d6
Stable Isotopes
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
--
Storage
Refer MSDS for complete information.
Hazard Information
Refer MSDS for complete information.
3-Hydroxy Bortezomib-d6 Product Information
3-Hydroxy Bortezomib-d6 is listed under Stable Isotopes. It is associated with - and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-96431.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
3-Hydroxy Bortezomib-d6
CAS No.
-
CAT No.
CS-T-96431
Molecular Formula
C19H19D6BN4O5
Molecular Weight
406.27
Category
API Family
Storage Condition
Refer MSDS for complete information.
SMILES
[2H]C([2H])([2H])C(C[C@@H](B(O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(C([2H])([2H])[2H])O
IUPAC Name
[(1R)-4,4,4-trideuterio-3-hydroxy-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]-3-(trideuteriomethyl)butyl]boronic acid
Hazard Compound
Refer MSDS for complete information.
Description
Overview
"3-Hydroxy Bortezomib-d6 is the isotope labelled analog of 3-Hydroxy Bortezomib (H818150); a metabolite of Bortezomib (B675700) which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer."
Synonyms
((R)-3-Hydroxy-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid-d6
Application Notes
"3-Hydroxy Bortezomib-d6 is the isotope labelled analog of 3-Hydroxy Bortezomib (H818150); a metabolite of Bortezomib (B675700) which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer."
References
"Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)"
