CAS No.
[1106685-84-0 (Unlabeled)]
Storage Condition
Refer MSDS for complete information
Synonyms
rac 4-Hydroxymethyl Ambrisentan-d5
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
rac 4-Hydroxymethyl Ambrisentan-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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rac 4-Hydroxymethyl Ambrisentan-d5 usage and description
4-Hydroxymethyl Ambrisentan D5 is a derivative of Ambrisentan, which is a selective endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension. The chemical formula of 4-Hydroxymethyl Ambrisentan D5 is C23H19D5N2O3 and its molecular weight is 397.51 g/mol. The compound is deuterated, meaning that it contains five deuterium atoms, which are heavier isotopes of hydrogen.
The usage of 4-Hydroxymethyl Ambrisentan D5 is mainly in the field of pharmacokinetics research, where it is used as a stable isotope-labeled internal standard for the quantification of Ambrisentan in biological samples. It is also used in pharmacodynamic studies to investigate the metabolism and elimination of Ambrisentan in the body.
The chemical information on 4-Hydroxymethyl Ambrisentan D5 includes its physical and chemical properties, such as its melting point, boiling point, solubility, and stability. The compound is a white to off-white powder that is soluble in dimethyl sulfoxide and methanol. It is stable under normal storage conditions and has a shelf life of at least two years.
In conclusion, 4-Hydroxymethyl Ambrisentan D5 is a useful compound in pharmacokinetics research, providing a stable isotope-labeled internal standard for the quantification of Ambrisentan in biological samples. Its chemical information, including its physical and chemical properties, is important for its proper handling and storage.
