Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Estradiol Hemihydrate Impurity C
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
4-Methyl-17-beta-Estradiol is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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4-Methyl-17-beta-Estradiol usage and description
4-Methyl-17-β-Estradiol is a synthetic estrogen that is used in the treatment of certain types of breast cancer in postmenopausal women. This compound is a derivative of estradiol, a naturally occurring hormone in females that regulates reproductive function. 4-Methyl-17-β-Estradiol mimics the effects of estradiol in the body and helps to slow down the growth of cancer cells that are stimulated by estrogen.
Chemically, 4-Methyl-17-β-Estradiol is a derivative of estradiol that has a methyl group attached to the C4 position of the A-ring. This modification gives the compound greater stability and makes it more resistant to metabolism by the liver. It also enhances its binding affinity for the estrogen receptor, which is responsible for the biological effects of estrogen in the body.
In terms of usage, 4-Methyl-17-β-Estradiol is typically administered as an oral medication, either alone or in combination with other drugs such as tamoxifen. The dosage and duration of treatment will depend on the individual patient and the severity of their cancer. Common side effects of this medication include hot flashes, vaginal dryness, and nausea.
Overall, 4-Methyl-17-β-Estradiol is an important medication in the treatment of certain types of breast cancer. Its chemical structure and mode of action make it an effective and well-tolerated option for many patients.