Impurity Product Detail

5-epi Emtricitabine

Chemical Properties and Information

Product Code: CS-T-21592 Impurity
5-epi Emtricitabine
API Family
Emtricitabine
Product Code
CS-T-21592

5-epi Emtricitabine

Emtricitabine Impurity
Stock Status: : Enquire Live

CAT No.
CS-T-21592
CAS No.
145986-26-1
Molecular Formula
C₈H₁₀FN₃O₃S
Molecular Weight
247.3
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
145986-26-1
Product Code
CS-T-21592
M.F.
C8H10FN3O3S
M.W.
247.3
Smiles
NC1=NC(N([C@@H]2O[C@@H](CO)SC2)C=C1F)=O
Category
Impurity
API Family
Emtricitabine
Storage Condition
Store at freezer (-20°C) for long term storage
IUPAC Name
"4-Amino-5-fluoro-1-((2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one"
References
Jeong, L., et al.: J. Med. Chem., 36, 181 (1993); Lim, S. et al.: Arch. Intern. Med., 166, 49 (2006); Smith, K., et al.: AIDS, 23, 1547 (2009)
Synonyms
5-Epi-Emtricitabine
Application Notes
5-epi Emtricitabine is an epimer of Emtricitabine (E525000), a nucleoside reverse transcriptase inhibitor approved for treatment of human immunodeficiency virus (HIV) 1, and also has antagonistic activity against the hepatitis B virus. 5-epi Emtricitabine is also used as a reagent for the synthesis of b-L-(2R,5S)- and a-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential HIV agents.
Purity by HPLC
99.31%
Hazard Compound
Refer MSDS for accurate information.
Overview
5-epi Emtricitabine is an epimer of Emtricitabine (E525000), a nucleoside reverse transcriptase inhibitor approved for treatment of human immunodeficiency virus (HIV) 1, and also has antagonistic activity against the hepatitis B virus. 5-epi Emtricitabine is also used as a reagent for the synthesis of b-L-(2R,5S)- and a-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential HIV agents.
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