Therapeutic Uses
Anti-Diabetic
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione, 586408-08-4
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione usage and description
7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is a chemical compound with the molecular formula C12H10N4O2. It is also known as BU-224 and is a potent inhibitor of the enzyme phosphodiesterase 4 (PDE4). PDE4 inhibitors have been shown to have therapeutic potential in a range of conditions such as asthma, chronic obstructive pulmonary disease (COPD), and inflammatory bowel disease (IBD).
The compound's structure consists of a purine ring with a but-2-yn-1-yl group attached at the 7 position and a methyl group at the 3 position. The purine ring is a bicyclic structure composed of a pyrimidine ring fused with an imidazole ring. The compound's melting point is 243-244°C, and it has a molecular weight of 234.23 g/mol.
In terms of usage, 7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is primarily used as a research chemical to investigate the role of PDE4 inhibition in various disease states. It is not currently approved for clinical use in humans. However, preclinical studies have shown promising results, and further research is underway to determine its potential as a therapeutic agent.
In conclusion, 7-(But-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is a potent PDE4 inhibitor with potential therapeutic applications in various disease states. Its chemical structure and properties make it a valuable tool for research in this area. However, its clinical use in humans is yet to be determined.
