Product Detail
7(R)-epi Carfilzomib (2S,4R)-diol
Carfilzomib Impurity
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category
Impurity
API Family
Carfilzomib
Storage
Refer MSDS for complete information.
Hazard Information
Refer MSDS for complete information.
7(R)-epi Carfilzomib (2S,4R)-diol Product Information
7(R)-epi Carfilzomib (2S,4R)-diol is listed under Impurity. It is associated with Carfilzomib and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-35245.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
7(R)-epi Carfilzomib (2S,4R)-diol
CAS No.
-
CAT No.
CS-O-35245
Molecular Formula
C40H59N5O8
Molecular Weight
737.93
Category
API Family
Storage Condition
Refer MSDS for complete information.
SMILES
CC(C)C[C@H](NC([C@@H](NC(CN1CCOCC1)=O)CCC2=CC=CC=C2)=O)C(N[C@H](CC3=CC=CC=C3)C(N[C@H](CC(C)C)C([C@@](C)(O)CO)=O)=O)=O
Hazard Compound
Refer MSDS for complete information.
Description
Overview
Carfilzomib (2S,4R)-Diol is an impurity of Carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
Synonyms
(S)-N-((R)-1-(((2S,4R)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
Application Notes
Carfilzomib (2S,4R)-Diol is an impurity of Carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
References
Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);
