Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(2R,3R,4R,5R)-2,3,4,5,6-Pentahydroxyhexyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate; Mannitol-1-yl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H -benzimidazol-2-yl}butanoate; Bendamustine Related Compound F
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Bendamustine D-Mannitol Ester is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Bendamustine D-Mannitol Ester usage and description
Bendamustine D-Mannitol Ester is an anticancer drug used in the treatment of chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). It is a prodrug of Bendamustine, a chemotherapy agent that acts by interfering with DNA replication and cell division, ultimately leading to cell death. The addition of Mannitol Ester to Bendamustine enhances its solubility and stability, allowing for more effective delivery to the target cells.
Bendamustine D-Mannitol Ester is typically administered intravenously and is metabolized by the liver into its active form, Bendamustine. The drug has a half-life of approximately 40 minutes and is excreted by the kidneys. The dosage and frequency of administration are determined by the patient's age, weight, and overall health status.
As with all chemotherapy drugs, Bendamustine D-Mannitol Ester has potential side effects, including nausea, vomiting, fatigue, and an increased risk of infection. Additionally, the drug may cause low blood cell counts, which can lead to anemia, bleeding, and an increased risk of infection.
In conclusion, Bendamustine D-Mannitol Ester is an effective chemotherapy drug used in the treatment of CLL and NHL. Its unique chemical composition allows for increased solubility and stability, leading to more effective delivery to target cells. While the drug has potential side effects, its benefits in treating cancer outweigh the risks for many patients.
