CAS No.
[1233921-74-8 (Freebase)]
Therapeutic Uses
Immunosuppressants
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
4-Amino-1-(2-deoxy-2,2-difluoro-b-D-erythro-pentofuranosyl)pyrimidin-2(1H)-one-1,3-15N2-13C hydrochloride
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Beta-Gemcitabine-13C,15N2 Hydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Beta-Gemcitabine-13C,15N2 Hydrochloride usage and description
ฮฒ-Gemcitabine 13C,15N2 Hydrochloride is a modified version of the drug Gemcitabine, which is commonly used to treat various types of cancer. The addition of carbon-13 and nitrogen-15 isotopes to the compound allows for more precise tracking and analysis of its distribution and metabolism within the body. This enables researchers to gain a better understanding of how the drug is working, and potentially identify ways to optimize its effectiveness.
Chemically, ฮฒ-Gemcitabine 13C,15N2 Hydrochloride is a nucleoside analogue, meaning it mimics the structure of the nucleosides that make up DNA. When the drug is taken up by cancer cells, it is incorporated into their DNA, disrupting their ability to divide and ultimately leading to cell death. This mechanism of action makes it particularly effective against rapidly dividing cancer cells.
The drug is typically administered intravenously, and the dose and frequency of treatment will depend on the type and stage of cancer being treated, as well as the patient's overall health. Common side effects of ฮฒ-Gemcitabine 13C,15N2 Hydrochloride include nausea, vomiting, fatigue, and decreased white blood cell count. As with all medications, it is important to follow the prescribed dosing instructions and to consult with a healthcare professional if any concerning side effects arise.
