CAS No.
[863239-61-6 (Unlabeled)]
API Family
Obeticholic acid
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Tauroobeticholic acid-D5
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
Tauro 6-ethylchenodeoxycholate-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Tauro 6-ethylchenodeoxycholate-d5 usage and description
Tauro 6-ethylchenodeoxycholate-d5 (TECDCA-d5) is a bile acid derivative that is commonly used in research and clinical settings to study liver and gastrointestinal functions. It is a deuterium-labeled analogue of taurochenodeoxycholic acid, which is a natural bile acid found in human bile. The d5 labeling of TECDCA-d5 allows researchers to track the metabolic fate of the bile acid in vivo using mass spectrometry.
TECDCA-d5 is often used in studies involving liver disease, cholestasis, and bile acid transport. It has been shown to have hepatoprotective effects in animal models of liver injury and has also been used to investigate the role of bile acids in lipid metabolism and insulin resistance. Additionally, TECDCA-d5 has been used to assess the kinetics of bile acid absorption and excretion in humans.
Chemically, TECDCA-d5 is a steroid molecule with a four-ring structure and a hydroxyl group at the 3-position. It is conjugated with taurine at the 24-position, which enhances its solubility and promotes its excretion. The ethyl group at the 6-position of TECDCA-d5 increases its hydrophobicity and alters its interactions with cellular membranes and transporters.
Overall, TECDCA-d5 is a valuable tool for investigating the physiological and pathological roles of bile acids in health and disease. Its unique deuterium labeling allows for precise quantification and tracking of the molecule in biological systems, making it a powerful analytical tool.
