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Erythromycin-N-Oxide



Erythromycin-N-Oxide Cas No.992-65-4
  • CAT. No.CS-CM-00085
  • CAS. No.992-65-4
  • Mol. F.C₃₇H₆₇NO₁₄
  • Mol. Wt.749.93 g/mol
  • Stock Status In Stock

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1
  • Synonyms:Erithromycin N-Oxide
  • Chemical Name:(2S,3R,4S,6R)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-3-hydroxy-N,N,6-trimethyloxan-4-amine oxide
  • Application Notes:"Erythromycin A N-oxide is a minor analogue of the erythromycin complex isolated from Saccharopolyspora erythraea. The N-oxide is a facile metabolite formed in vivo which can revert to erythromycin A under reducing conditions. Despite its synthetic preparation in the 1950s, the biological activity of erythromycin A N-oxide has not been extensively studied.Erythromycin. I. Properties and degradation studies."
  • Product Category:Erythromycin Impurities

    Erythromycin-N-Oxide is identified by CAS No. 992-65-4 and is chemically known as Erithromycin N-Oxide, IUPAC Name: (2S,3R,4S,6R)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-3-hydroxy-N,N,6-trimethyloxan-4-amine oxide.

    Erythromycin-N-Oxide is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Erythromycin.


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