Storage Condition
Refer MSDS for complete information
Synonyms
2-((1r,4r)-4-(4-chlorophenyl-2,3,5,6-d4)cyclohexyl)-3-hydroxynaphthalene-1,4-dione
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Atovaquone-D4 (4-chlorophenyl-2,3,5,6-d4) is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Atovaquone-D4 (4-chlorophenyl-2,3,5,6-d4) usage and description
Atovaquone-D4 (4-chlorophenyl-2,3,5,6-d4) is a deuterated form of the antimalarial drug Atovaquone. It is used to treat and prevent malaria caused by Plasmodium falciparum. Atovaquone-D4 is a lipophilic compound that works by inhibiting mitochondrial electron transport in the parasite, thereby preventing energy production and eventually leading to the death of the parasite.
Atovaquone-D4 is administered orally in the form of tablets or suspension. The dosage and duration of treatment depend on the severity of the infection, age, weight, and medical history of the patient. Atovaquone-D4 is usually given in combination with other antimalarial drugs such as proguanil or pyrimethamine to prevent the development of drug-resistant strains of the parasite.
The chemical structure of Atovaquone-D4 is similar to that of ubiquinone, a natural component of the mitochondrial electron transport chain. Atovaquone-D4 is a substituted naphthoquinone with a chlorophenyl group at position 4. The deuterated form of the compound contains four deuterium atoms, which replace four hydrogen atoms in the molecule.
Atovaquone-D4 has a molecular weight of 315.81 g/mol and a melting point of 210-214ยฐC. It is slightly soluble in water but highly soluble in organic solvents such as ethanol, methanol, and chloroform. The compound is stable under normal storage conditions and has a shelf-life of several years. Atovaquone-D4 is a potent antimalarial drug with low toxicity and is widely used in the treatment of malaria in both adults and children.