API Family
Hydrocortisone
Storage Condition
Refer MSDS for complete information
Synonyms
6-€‹beta-€‹Hydroxycortisol-d4
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
6b-Hydroxy Cortisol-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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6b-Hydroxy Cortisol-d4 usage and description
6b-Hydroxy Cortisol-d4 is a stable isotope labelled analogue of the endogenous hormone, cortisol. It is used as a research tool in studies investigating the metabolic fate of cortisol in vivo or in vitro. The deuterium label on the D4 position of the molecule allows for identification and quantification of the labelled compound in biological samples using mass spectrometry techniques.
Cortisol is a glucocorticoid hormone that regulates various physiological processes, including metabolism, stress response, and immune function. The hydroxylation of cortisol at the 6b position is a key step in the metabolism of cortisol, leading to the formation of cortisone. The measurement of 6b-hydroxy cortisol in biological fluids is used as a biomarker of cortisol metabolism.
The chemical formula of 6b-Hydroxy Cortisol-d4 is C21H28D4O5, and its molecular weight is 384.5 g/mol. The compound is available as a powder or solution for research purposes. It is stable under normal conditions and can be stored at -20°C for long-term use.
In conclusion, 6b-Hydroxy Cortisol-d4 is a valuable research tool for investigating the metabolism of cortisol. Its stable isotope label allows for accurate identification and quantification of the compound in biological samples. The compound is safe and stable under normal conditions, making it suitable for use in various research settings.
