CAS No.
[503614-92-4(Unlabelled)]
Storage Condition
Refer MSDS for complete information
Synonyms
Apixaban Acid-13C, 503614-92-4(Unlabelled)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Apixaban Acid-13C is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Apixaban Acid-13C usage and description
Apixaban Acid-13C is a stable isotope labeled analog of Apixaban, a novel oral anticoagulant used for the treatment and prevention of thromboembolic disorders. Apixaban Acid-13C is synthesized with a high degree of isotopic purity and is commonly used in pharmacokinetic studies to evaluate the metabolic fate of Apixaban.
Apixaban Acid-13C belongs to a class of drugs known as direct oral anticoagulants (DOACs), which inhibit the activity of Factor Xa, a key enzyme involved in the blood clotting cascade. By inhibiting Factor Xa, Apixaban Acid-13C effectively prevents the formation of blood clots, thereby reducing the risk of stroke, deep vein thrombosis, and pulmonary embolism.
The chemical formula of Apixaban Acid-13C is C25H22C13N5O4S, and its molecular weight is 555.6 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents such as methanol and dimethyl sulfoxide.
Apixaban Acid-13C is metabolized primarily in the liver by cytochrome P450 enzymes, and its half-life is approximately 12 hours. The pharmacokinetics of Apixaban Acid-13C are similar to those of Apixaban, and it is excreted primarily in the feces.
In conclusion, Apixaban Acid-13C is a valuable tool for investigating the pharmacokinetics and metabolism of Apixaban, a widely used anticoagulant. Its stable isotopic labeling allows for accurate and sensitive detection in biological samples, making it an essential component of drug development and clinical research.