Bleomycin Sulfate (Mixture of Bleomycin A2 & Bleomycin B2)

9041-93-4

CS-O-00968

C₅₅H₈₆N₁₇O₂₅S₄

1513.63

O[C@H]1[C@H](OC(N)=O)[C@H](O)[C@@H](O[C@H]2[C@@H](O)[C@H](O)[C@H](CO)O[C@H]2OC([C@H](NC(C3=NC([C@@H](NC[C@H](N)C(N)=O)CC(N)=O)=NC(N)=C3C)=O)C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@@H]([C@H](O)C)C(NCCC4=NC(C5=NC(C(NCCC[S+](C)C)=O)=CS5)=CS4)=O)=O)=O)C6=CNC=N6)O[C@@H]1CO.O=S(O)(O)=O

Impurity

Bleomycin Sulfate

Store at refrigerator (2-8°C) for long term storage

(3-(2'-((3S,6R,7S,8S,11S)-1-(6-amino-2-((S)-3-amino-1-(((S)-2,3- diamino-3-oxopropyl)amino)-3-oxopropy1)-5-methylpyrimidin-4-y1)-3- ((R)-(((2R,3S,4R,5R,6S)-3-(((2S,3S,4R,5S,6S)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyptetrahydro-2H-pyran-2-ypoxy)-4,5-dihydroxy-6-(hydroxymethyptetrahydro-2H-pyran-2-ypoxy)(1H-imidazol¬5-yOmethyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12- tetraoxo-2,5,10,13-tetraazapentadecan-15-y1)-[2,4'-bithiazole]-4-carboxamido)propyl)dimethylsulfonium hydrogen sulfate

"Umezawa; et al,: J, Antibiot,; 19; 200 (1966); Burger; R,M,; et al,: Life Sci,; 28; 715 (1981); Marugesan; N,; et al,: J, Biol, Chem,; 257; 8600 (1982); Saito; S,; et al,: J, Antibiot,; 36; 92 (1983);"

Not available

A group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically.

99.3

Refer MSDS for accurate information.