M.F.
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Therapeutic Uses
Immunosuppressants
API Family
Mycophenolate Mofetil
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
(E)-6-(4-hydroxy-6-(methoxy-13C-d3)-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
Yes -Refer MSDS for accurate information
Mycophenolic acid-13C,d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Mycophenolic acid-13C,d3 usage and description
Mycophenolic Acid 13C-d3 is a stable isotope-labeled form of Mycophenolic Acid (MPA), which is an immunosuppressive drug used to prevent rejection in organ transplant patients. MPA works by inhibiting the proliferation of T and B cells, which are responsible for rejecting transplanted organs.
The usage of Mycophenolic Acid 13C-d3 is primarily in pharmacokinetic studies, where it is used as a tracer to determine the metabolism and distribution of Mycophenolic Acid in the body. The stable isotope-labeled form of the drug allows for accurate and precise quantification of MPA in biological samples using mass spectrometry techniques.
Chemically, Mycophenolic Acid 13C-d3 is synthesized using a combination of organic chemistry techniques and isotope labeling. The drug contains three carbon atoms that are substituted with stable isotopes of carbon-13, which do not affect the pharmacological properties of the drug.
The use of Mycophenolic Acid 13C-d3 in pharmacokinetic studies has provided valuable insights into the metabolism and distribution of the drug in the body, leading to improved dosing regimens and reduced side effects. Furthermore, the stable isotope-labeled form of the drug can also be used in drug-drug interaction studies to determine the effects of other drugs on the metabolism of Mycophenolic Acid.