Product Detail
Rifampicin
Rifampicin API
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
API
API Family
Rifampicin
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Rifampicin Product Information
Rifampicin is listed under API. It is associated with Rifampicin and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-02232.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Rifampicin
CAS No.
13292-46-1
CAT No.
CS-O-02232
Molecular Formula
C43H58N4O12
Molecular Weight
822.94
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
CC(O[C@@H]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C(N1)=O)[C@H](C)[C@@H](OC)/C=C/O[C@](O2)(C)C(C3=C2C(C)=C(O)C4=C3C(O)=C(/C=N/N5CCN(C)CC5)C1=C4O)=O)=O
IUPAC Name
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms."
Synonyms
(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate
Application Notes
"A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms."
References
"Gidoh; M, et al,: Nip, Rai Gak, Zas,; 47; 110 (1978); Konrad; P, et al,:clin, Immunol, Immunopathol,; 46;162 (1988); Prasad; B, et al,: J, Pharmc, Biomed, Anal,; 50; 475 (2009);"
