Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Artemos-D3; Artenam-D3; Artesaph-D3
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Artemether-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Artemether-d3 usage and description
Artemether D3 is a synthetic derivative of artemisinin, a natural product isolated from the Chinese medicinal plant Artemisia annua. It is a potent antimalarial drug used in the treatment of uncomplicated malaria caused by Plasmodium falciparum, a species of the parasite that is resistant to many other antimalarial drugs. The addition of three deuterium atoms to the structure of artemether allows for its use as a stable isotope internal standard in pharmacokinetic studies.
Artemether D3 acts by inhibiting the growth and replication of the malaria parasite in the blood. Its mechanism of action involves the formation of free radicals and the generation of reactive oxygen species, which damage the parasite's cell membrane and proteins, leading to its death. The drug is effective against both the blood stages and the liver stages of the parasite's life cycle, making it an important tool in the fight against malaria.
The recommended dosage of artemether D3 varies depending on the age and weight of the patient, as well as the severity of the infection. It is typically administered in combination with another antimalarial drug, such as lumefantrine or mefloquine, to reduce the risk of drug resistance. The drug is generally well-tolerated, although some common side effects include nausea, vomiting, and dizziness.
In conclusion, artemether D3 is a potent and effective antimalarial drug that is widely used in the treatment of malaria. Its stable isotope properties make it an important tool in pharmacokinetic studies, and its mechanism of action is well-understood. With continued research and development, artemether D3 may play an increasingly important role in the fight against malaria and other parasitic diseases.
