Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
(8S,9S,10R,11S,13S,14S,17R)-chloromethyl 17-((ethoxycarbonyl)oxy)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate-D5
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Loteprednol Etabonate-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Loteprednol Etabonate-d5 usage and description
Loteprednol Etabonate D5 is a synthetic corticosteroid used as a treatment for a variety of ocular inflammatory conditions. It is a deuterated form of Loteprednol Etabonate, which means that it contains five atoms of deuterium in its molecular structure. This modification enhances the pharmacokinetic properties of the drug, providing longer-lasting and more consistent therapeutic effects.
The drug is administered as an ophthalmic suspension or gel and works by reducing inflammation and swelling in the eye. This helps to relieve symptoms such as redness, itching, and pain. Loteprednol Etabonate D5 is particularly effective in treating conditions such as allergic conjunctivitis, anterior uveitis, and keratitis.
Chemically, Loteprednol Etabonate D5 is a halogenated corticosteroid that contains a ketone group, a double bond, and a chlorine atom. Its molecular formula is C22H29ClO6D5, and its molecular weight is 472.04 g/mol. The drug is soluble in water and ethanol but is insoluble in most organic solvents.
In terms of safety, Loteprednol Etabonate D5 has been shown to have a favorable side effect profile, with minimal ocular and systemic adverse effects reported. However, as with any medication, it should only be used as directed by a healthcare professional.