Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
3-Butylamino-4-(2,3,4,5,6-pentadeuteriophenoxy)-5-sulfamoylbenzoic acid
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
Bumetanide-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Bumetanide-d5 usage and description
Bumetanide D5 is a deuterated version of the diuretic drug Bumetanide, which is primarily used to treat edema caused by congestive heart failure, liver cirrhosis, and kidney disease. Bumetanide D5 is used for the same purpose, but with the added benefit of increased selectivity and potency due to the incorporation of deuterium isotopes.
The chemical formula of Bumetanide D5 is C16H13D5N2O5S, and it has a molecular weight of 365.49 g/mol. The drug works by inhibiting the sodium-potassium-chloride cotransporter in the ascending loop of Henle in the kidneys, leading to increased excretion of sodium, potassium, and chloride ions in the urine. This reduces the water retention in the body and helps to reduce swelling and edema.
The recommended dosage of Bumetanide D5 is typically 0.5 to 2 mg per day, which can be adjusted based on individual patient response. The drug is administered orally or intravenously and is usually well-tolerated, although some patients may experience side effects such as dizziness, headache, and nausea.
In conclusion, Bumetanide D5 is a potent and selective diuretic drug that can effectively treat edema caused by various medical conditions. Its deuterated form provides additional benefits in terms of increased potency and selectivity. However, it should only be used under the guidance of a qualified healthcare professional and with close monitoring of its effects and potential side effects.
