Therapeutic Uses
Anti-Emetics
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Cinnarizine-d8 Dihydrochloride, 1276545-36-8
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Cinnarizine-d8 Dihydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Cinnarizine-d8 Dihydrochloride usage and description
Cinnarizine D8 Dihydrochloride is a deuterated form of Cinnarizine, a medication that is primarily used to treat nausea, dizziness, and motion sickness. The deuterated form, Cinnarizine D8 Dihydrochloride, is used in scientific research and drug development studies as a stable isotope-labeled standard for quantitative analysis by mass spectrometry.
The chemical formula of Cinnarizine D8 Dihydrochloride is C26H28D8Cl2N3, and its molecular weight is 489.51 g/mol. It has a melting point of 220-225°C and is soluble in water and ethanol.
The mechanism of action of Cinnarizine D8 Dihydrochloride involves the inhibition of calcium channels, which reduces the influx of calcium ions into cells. This leads to a decrease in the release of neurotransmitters and a reduction in the sensitivity of the vestibular system in the inner ear, resulting in a reduction in nausea and dizziness.
Cinnarizine D8 Dihydrochloride is typically administered orally, with the recommended dosage varying depending on the patient's age and condition. It is generally well-tolerated, with common side effects including drowsiness, dry mouth, and constipation.
In conclusion, Cinnarizine D8 Dihydrochloride is an important tool for scientific research and drug development, and its use can help to advance our understanding of the mechanisms of action of drugs and their effects on the body.
