Therapeutic Uses
Immunosuppressants
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl-2,3,5,6-d4)but-2-enamide
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Teriflunomide-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
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Teriflunomide-d4 usage and description
Teriflunomide D4 is a deuterated version of the drug Teriflunomide, which is used to treat relapsing multiple sclerosis. It works by inhibiting an enzyme called dihydroorotate dehydrogenase, which is necessary for the proliferation of T and B lymphocytes. This results in a decrease in the inflammatory response in the central nervous system, which is a key factor in the development of multiple sclerosis.
Teriflunomide D4 is used in research and clinical settings as a stable isotopic internal standard for the quantification of Teriflunomide in biological samples. Deuterated compounds are used as internal standards because they have identical chemical properties to their non-deuterated counterparts, but have a different mass. This allows for accurate and precise measurement of the drug in samples, as the deuterated internal standard can be easily distinguished from the endogenous compound.
The chemical formula for Teriflunomide D4 is C12H7D4F3N2O2, and it has a molecular weight of 279.24 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide, ethanol, and acetonitrile.
In conclusion, Teriflunomide D4 is a valuable tool in the quantification of Teriflunomide in biological samples, and its usage in research and clinical settings is important for understanding the pharmacokinetics and pharmacodynamics of this drug in the treatment of multiple sclerosis.
