CAS No.
402957-28-2(Unlabeled)
Smiles
O=C(NC1C([2H])([2H])C1([2H])[2H])C([C@H](CCC)NC([C@@H]2[C@]3([H])[C@](CCC3)([H])CN2C([C@H](C(C)(C)C)NC([C@H](C4CCCCC4)NC(C5=NC=CN=C5)=O)=O)=O)=O)=O
Therapeutic Uses
Antiretroviral / Anti-HIV
IUPAC Name
(1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-((cyclopropyl-2,2,3,3-d4)amino)-1,2-dioxohexan-3-yl)octahydrocyclopenta[c]pyrrole-1-carboxamide
References
"Kieffer; T,; et al,: Hepatology; 46; 631 (2007); Zhou; Y,; et al,: Antimicrob, Agents Chemother,; 52; 110 (2008); Hezode; C,; et al,: N, Engl, J, Med,; 360; 1839 (2009);"
Synonyms
LY 570310-d4; MP 424-d4; VRT 111950-d4; VX 950-d4
Application Notes
"Labeled Telaprevir, intended for use as an internal standard for the quantification of Telaprevir by GC- or LC-mass spectrometry."
Hazard Compound
Refer MSDS for complete information
"Labeled Telaprevir, intended for use as an internal standard for the quantification of Telaprevir by GC- or LC-mass spectrometry."
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Telaprevir-d4 usage and description
Telaprevir D4 is a deuterated form of Telaprevir, a drug used in the treatment of chronic hepatitis C virus (HCV) infection. The deuterated form of the drug is used for pharmacokinetic studies and investigations. The drug works by inhibiting the viral protease enzyme, which is essential for the replication of the virus.
Telaprevir D4 is administered orally, usually in combination with other drugs, in the form of a tablet. The recommended dosage is 750 mg three times a day, taken with food. The drug has a half-life of approximately 4 hours and is metabolized in the liver.
Chemically, Telaprevir D4 is a deuterated form of the parent drug Telaprevir. The deuterated form is created by replacing hydrogen atoms with deuterium atoms, which are stable isotopes of hydrogen. This modification alters the pharmacokinetics of the drug, resulting in slower clearance from the body, which may lead to improved efficacy and tolerability.
Clinical studies have shown that the use of Telaprevir D4 results in a reduction in the viral load in patients with chronic HCV infection. The drug has also been found to be well-tolerated, with minor side effects such as fatigue and headache.
In conclusion, Telaprevir D4 is an important tool for investigating the pharmacokinetics and efficacy of Telaprevir in the treatment of chronic HCV infection. It is a safe and effective drug that has the potential to improve the lives of millions of people suffering from this disease.
