CAS No.
[87249-11-4(Unlabeled)]
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
(S)-2-(1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl-3,3,4,4-d4)acetic acid
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
(S)-Etodolac-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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(S)-Etodolac-d4 usage and description
(S)-Etodolac D4 is a deuterated form of the nonsteroidal anti-inflammatory drug (NSAID) Etodolac. This compound is used as a reference standard in analytical testing and research studies. It is commonly used in pharmacokinetic studies to determine the rate and extent of drug absorption, distribution, metabolism, and excretion in the body.
Etodolac is known for its ability to inhibit the production of prostaglandins, which are inflammatory mediators that cause pain, swelling, and fever. It achieves this by blocking the activity of the cyclooxygenase (COX) enzymes, which are responsible for the synthesis of prostaglandins.
(S)-Etodolac D4 has the same chemical structure as Etodolac, except for the substitution of four deuterium atoms in the molecule. Deuterium is a stable isotope of hydrogen, and its incorporation into the molecule can help in the identification and quantification of the drug in biological samples.
The chemical formula of (S)-Etodolac D4 is C17H12D4ClNO3, and its molecular weight is 319.80 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents like methanol, ethanol, and acetone.
In conclusion, (S)-Etodolac D4 is a valuable tool in drug development and research that can provide critical insights into the pharmacokinetics and pharmacodynamics of Etodolac and other NSAIDs.
