CAS No.
[404844-02-6(Unlabeled)]
Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide-2,3,5,6-d4
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Desmethyl Imatinib-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Desmethyl Imatinib-d4 usage and description
Desmethyl imatinib D4 is a chemical compound that is commonly used as a research tool in the development of new drugs for the treatment of cancer. This compound is a deuterated analog of Desmethyl imatinib, which is a metabolite of imatinib, a tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML) and other cancers.
Desmethyl imatinib D4 is often used in pharmacokinetic studies to determine the metabolism and elimination of the compound in vivo. The deuterium labeling of the compound allows for accurate measurement of its pharmacokinetic properties, which can aid in the development of more effective cancer treatments.
Chemically, Desmethyl imatinib D4 is a derivative of imatinib, with the addition of deuterium atoms at specific positions in the molecule. The compound has a molecular weight of 514.6 g/mol and a molecular formula of C29H29D4N7O. It is a white to off-white powder that is soluble in dimethylsulfoxide, methanol, and ethanol.
In conclusion, Desmethyl imatinib D4 is a valuable research tool in the development of new cancer treatments. Its deuterium labeling allows for accurate measurement of pharmacokinetic properties, which can aid in the development of more effective drugs for the treatment of cancer.