CAS No.
289480-64-4 (unlabeled)
M.F.
CโโยนยณCโHโโDNaOโ
Smiles
O=[13C]([O-])[13CH2]OC1=C2C[C@@]3([H])C[C@@]([2H])(O)[C@H](CC[C@@H](O)CCCCC)[C@@]3([H])CC2=CC=C1.[Na+]
Therapeutic Uses
Prostaglandins
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
IUPAC Name
sodium 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl-2-d]oxy]acetate-1,2-13C2
References
"Journal of Pharmacy and Pharmacology, 1995 Apr; Thrombosis Research, 1993 "
Synonyms
Treprostinil 13C2,d1 Sodium
Application Notes
"Labeled Treprostinil, intended for use as an internal standard for the quantification of Treprostinil by GC- or LC-mass spectrometry."
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information
"Labeled Treprostinil, intended for use as an internal standard for the quantification of Treprostinil by GC- or LC-mass spectrometry."
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Treprostinil-13C2,d1 Sodium usage and description
Treprostinil is a medication used to treat pulmonary arterial hypertension (PAH). PAH is a rare and serious condition characterized by high blood pressure in the arteries of the lungs, which can lead to heart failure and other complications. Treprostinil works by relaxing and widening the blood vessels in the lungs, improving blood flow and reducing the workload on the heart.
Treprostinil 13C2 D1 Sodium Salt is a stable isotope-labeled form of treprostinil. It is used in pharmacokinetic studies to track the absorption, distribution, metabolism, and excretion of the medication in the body. The stable isotope labeling allows for accurate and sensitive detection of treprostinil in biological samples, which is important for understanding its pharmacological effects.
Treprostinil 13C2 D1 Sodium Salt is chemically similar to the non-labeled treprostinil, with the addition of two carbon-13 isotopes and one deuterium isotope. These isotopes do not significantly alter the pharmacological properties of the medication, but they do allow for more precise measurement and analysis.
In summary, Treprostinil 13C2 D1 Sodium Salt is an important tool in pharmacokinetic studies of treprostinil, allowing for accurate and sensitive measurement of the medication's effects in the body.