Product Detail
Exenatide-d5 Acetate
Exenatide Stable Isotopes
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
Exenatide
Storage
Store at freezer (-20°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Exenatide-d5 Acetate Product Information
Exenatide-d5 Acetate is listed under Stable Isotopes. It is associated with Exenatide and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-03498.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Exenatide-d5 Acetate
CAS No.
141732-76-5(Unlabeled)
CAT No.
CS-O-03498
Molecular Formula
C₁₈₄H₂₇₇D₅N₅₀O₆₀S.C₂H₄O₂
Molecular Weight
4251.65
Category
API Family
Storage Condition
Store at freezer (-20°C) for long term storage
SMILES
[2H]C([2H])([C@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(C([2H])(NC([C@@H](N)CC1=CNC=N1)=O)[2H])=O)CCC(O)=O)=O)=O)[C@H](O)C)=O)CC2=CC=CC=C2)=O)[C@H](O)C)=O)CO)=O)CC(O)=O)=O)CC(C)C)=O)CO)=O)CCCCN)=O)CCC(N)=O)=O)CCSC)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N3CCC[C@H]3C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N4CCC[C@H]4C(N5CCC[C@H]5C(N6CCC[C@H]6C(N[C@H](C(N)=O)CO)=O)=O)=O)=O)C)=O)=O)CO)=O)CO)=O)=O)=O)=O)CC(N)=O)=O)CCCCN)=O)CC(C)C)=O)CC7=CNC8=CC=CC=C87)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC9=CC=CC=C9)=O)CC(C)C)=O)CCCNC(N)=N)=O)C)[2H].O=CO
IUPAC Name
His-Gly-Glu-Gly-Thr-Phe(D5)-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-
Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2.CH3COOH
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"Exenatide-d5 Acetate is labelled Exenatide Acetate which causes an increase in acinar cAMP without stimulating amylase release. Exenatide has found use as a medication of diabetes II.;Labeled Exenatide, intended for use as an internal standard for the quantification of Exenatide by GC- or LC-mass spectrometry."
Synonyms
(4S)-5-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-4-amino-1-[[2-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-2-oxoethyl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-4,4,4-trideuterio-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]amino]-2,2-dideuterioacetyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoic acid;formic acid
Application Notes
"Exenatide-d5 Acetate is labelled Exenatide Acetate which causes an increase in acinar cAMP without stimulating amylase release. Exenatide has found use as a medication of diabetes II.;Labeled Exenatide, intended for use as an internal standard for the quantification of Exenatide by GC- or LC-mass spectrometry."
References
"Pugazhenthi; U, et al,: Diabetol,; 53; 2357 (2010); Li; C, et al,: Bioche;, Biophys, Res, Comm,; 400; 563 (2010); Lupi; R, et al,: Diab, Obes, Metab,; 10; 515 (2008); Kim; T,H, et al,: Bioconj, Chem,; 22; 625 (2011);"
