CAS No.
[5630-53-5(Unlabeled)]
M.F.
CโโHโโDโ
Oโ
Therapeutic Uses
Anti-Migraines
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
(7R,8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-7-(methyl-d3)-1,2,4,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one-16,16-d2
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Tibolone-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Tibolone-d5 usage and description
Tibolone D5 is a synthetic steroid hormone that is commonly used in hormone replacement therapy (HRT) for postmenopausal women. It is a derivative of nortestosterone and has both estrogenic and progestogenic properties. Tibolone D5 is a deuterated form of Tibolone, which is a medication that has been used in Europe and other parts of the world for over 20 years.
The chemical structure of Tibolone D5 is similar to that of other steroid hormones, but it has been modified to reduce its androgenic effects. It is metabolized in the liver to form three active compounds: 3ฮฑ- and 3ฮฒ-hydroxytibolone, and the ฮ4-isomer of tibolone. These active compounds act as agonists at estrogen, progesterone, and androgen receptors, depending on the tissue.
Tibolone D5 is used to relieve symptoms of menopause, such as hot flashes, vaginal dryness, and mood swings. It also helps prevent bone loss, which is a common problem for postmenopausal women. Additionally, it has been shown to have a positive effect on lipid metabolism, reducing LDL cholesterol and increasing HDL cholesterol.
Like all medications, Tibolone D5 has potential side effects, including headaches, dizziness, and breast tenderness. It may also increase the risk of developing endometrial cancer and breast cancer, although the risk is considered to be low. Overall, Tibolone D5 is a useful medication for postmenopausal women who are experiencing symptoms of menopause and want to maintain their bone health.
