Smiles
O=C1N(C)[C@@]2(CO)C(N3[C@@]1(SS2)CC4=CC=C[C@H](O)C34)=O
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(3R,6S,10aR)-6-Hydroxy-3-(hydroxymethyl)-2-methyl-2,3,5a,6-tetrahydro-10H-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione
References
"Takahashi; M,; et al,: J, Antibiotics,; 65; 263 (2012); Li,; Y,G,; et al,: Biochem, Biophy, Rsch, Commun,; 422; 85 (2012); Zhang; H,C,; et al,: Applied; Mech, Mater,; 178; 783 (2012); Scharf; D,H,; et al,: Appl, Microbiol, Biotechnol,; 93; 467 (2012)"
Synonyms
Aspergillin; (3R,5aS,6S,10aR)-2,3,5a,6-Tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione (ACI); 10H-3,10a-Epidithiopyrazino[1,2-a]indole-1,4-dione, 2,3,5a,6-tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-, [3R-(3α,5aβ,6β,10aα)]- (8CI); Gliotoxin (6CI, 7CI)
Application Notes
"Gliotoxin is a sulfur-containing mycotoxin produced by species of fungi and pathogens of humans. Gliotoxin exhibits inhibitory activities against histone H3K9 methyltransferase, a key enzyme in the re gulation of transcriptional activity by writing epigen"
Hazard Compound
Refer MSDS for accurate information.
