Metabolite Product Detail

Loperamide N-oxide

Chemical Properties and Information

Product Code: CS-O-06077 Metabolite
Loperamide N-oxide
API Family
Loperamide
Product Code
CS-O-06077

Loperamide N-oxide

Loperamide Metabolite
Stock Status: In Stock
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CAT No.
CS-O-06077
CAS No.
106900-12-3
Molecular Formula
C₂₉H₃₃ClN₂O₃
Molecular Weight
493.04
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
106900-12-3
Product Code
CS-O-06077
M.F.
C₂₉H₃₃ClN₂O₃
M.W.
493.04
Smiles
O=C(N(C)C)C(C1=CC=CC=C1)(C2=CC=CC=C2)CC[N]3(CCC(O)(C4=CC=C(Cl)C=C4)CC3)=O
Category
Metabolite
API Family
Loperamide
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
4-(4-chlorophenyl)-1-(4-(dimethylamino)-4-oxo-3,3-diphenylbutyl)-4-hydroxypiperidine 1-oxide
References
"Lavrijsen; K,; et al,: Drug Metab, Dispos,; 23; 354"
Synonyms
Loperamide EP Impurity F
Application Notes
Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.
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