CAS No.
[107220-28-0(Unlabeled)]
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(2R)-2'-(Methyl-d3)-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]-2'-d hydrochloride
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Cevimeline-d4 Hydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Cevimeline-d4 Hydrochloride usage and description
Cevimeline D4 hydrochloride is a medication that is used to treat symptoms associated with dry mouth caused by Sjögren's syndrome. It is a cholinergic agonist that works by stimulating the production of saliva. Cevimeline D4 hydrochloride is typically administered orally in the form of a capsule or tablet.
Chemically, Cevimeline D4 hydrochloride is a selective muscarinic M1 and M3 receptor agonist. It has a molecular formula of C10H18D4ClN2O2 and a molecular weight of 232.73 g/mol. Its chemical structure is similar to acetylcholine, a neurotransmitter that plays a key role in the parasympathetic nervous system.
Cevimeline D4 hydrochloride is metabolized in the liver and excreted through the kidneys. It has a half-life of approximately 2-3 hours. It is important to note that Cevimeline D4 hydrochloride may interact with other medications, including anticholinergic drugs, and should be used with caution in patients with certain medical conditions, such as asthma, gastrointestinal obstruction, or urinary tract obstruction.
In clinical trials, Cevimeline D4 hydrochloride has been shown to significantly improve symptoms of dry mouth in patients with Sjögren's syndrome. Common side effects of Cevimeline D4 hydrochloride include sweating, nausea, diarrhea, and headaches.