Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
2-Chloro-5-(4,5,6,7-tetradeuterio-1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Chlorthalidone-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Chlorthalidone-d4 usage and description
Chlorthalidone D4 is a deuterated form of chlorthalidone, which is a diuretic medication used to treat hypertension, congestive heart failure, and kidney disease. It works by increasing urine production, which helps to reduce excess salt and water in the body, thereby lowering blood pressure and decreasing the workload on the heart.
Chlorthalidone D4 is chemically identical to chlorthalidone, but with four of its hydrogen atoms replaced by deuterium atoms. This makes it useful in pharmacokinetic studies, where researchers can use it to track the drug's metabolism and distribution in the body. It is also used in forensic toxicology to identify the presence of chlorthalidone in biological samples.
The recommended dose of chlorthalidone D4 varies depending on the individual's condition, but typically ranges from 12.5 to 50 mg per day. It is usually taken orally once a day, preferably in the morning to avoid interrupting sleep with frequent urination.
Like chlorthalidone, chlorthalidone D4 can cause side effects such as dizziness, headache, nausea, and electrolyte imbalances. It may also interact with other medications, so it is important to inform the prescribing doctor of any other drugs being taken. Chlorthalidone D4 should not be used during pregnancy or breastfeeding.