Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
4,4'-Sulfonylbis(benzen-2,3,5,6-d4-amine)
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
Yes -Refer MSDS for accurate information
Dapsone-d8 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Dapsone-d8 usage and description
Dapsone D8 is a deuterated form of dapsone, an antibacterial and anti-inflammatory drug used to treat a variety of skin conditions, including leprosy, dermatitis herpetiformis, and acne vulgaris. Deuterated drugs are modified versions of existing drugs where some of the hydrogen atoms are replaced with deuterium, a stable, non-radioactive isotope of hydrogen. This modification can improve the drug's efficacy, safety, and pharmacokinetics.
Dapsone D8 has the same chemical formula as dapsone, C12H8D8N2O2S, but with eight deuterium atoms replacing eight hydrogen atoms. Deuterium is twice as heavy as hydrogen, which can affect the drug's metabolism, distribution, and elimination in the body. Studies have shown that dapsone D8 has a longer half-life and reduced toxicity compared to dapsone in animal models.
Dapsone D8 is typically administered orally in tablet form, with a recommended dosage of 50-100 mg per day, depending on the patient's condition and response to treatment. It works by inhibiting the synthesis of dihydrofolic acid, a precursor to DNA and RNA, thereby preventing the growth and replication of bacteria and reducing inflammation.
While dapsone D8 is generally well-tolerated, it can cause side effects such as nausea, vomiting, headache, and dizziness. It can also interact with other drugs, including rifampin, phenobarbital, and anticonvulsants, and should be used with caution in patients with glucose-6-phosphate dehydrogenase deficiency. Overall, dapsone D8 is a promising drug candidate with potential applications in treating a variety of skin disorders.
