Therapeutic Uses
Anti-Migraines
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
(2S,3S)-5-(2-(bis(methyl-d3)amino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Diltiazem-d6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Diltiazem-d6 usage and description
Diltiazem D6 is a deuterated form of the calcium channel blocker Diltiazem. It is commonly used in analytical research to determine the bioavailability, metabolism, and pharmacokinetics of Diltiazem in the body.
Diltiazem D6 works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to decreased contractility and relaxation of the blood vessels. This results in a reduction in blood pressure and increased oxygen supply to the heart.
The chemical structure of Diltiazem D6 is similar to that of Diltiazem, with the exception of six deuterium atoms that are substituted for hydrogen atoms. This modification allows for more accurate and sensitive detection of the drug in biological samples, as well as a more precise understanding of its metabolic pathways and excretion.
In terms of safety and side effects, Diltiazem D6 has similar properties to Diltiazem. It is generally well-tolerated, but can cause dizziness, headache, and constipation in some patients. It may also interact with other medications, so it is important to consult a healthcare provider before use.
Overall, Diltiazem D6 is a valuable tool for researchers studying the pharmacology and pharmacokinetics of Diltiazem. Its deuterated structure allows for accurate measurement and analysis of the drug in biological samples, leading to a better understanding of its effects and potential applications in clinical settings.