Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
Axilur-d3; Trideuteriomethyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Fenbendazole-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Fenbendazole-d3 usage and description
Fenbendazole D3 is a deuterated version of the anthelmintic drug Fenbendazole. The deuterium substitution in Fenbendazole D3 provides a unique tool for researchers to study the pharmacokinetics (PK) and metabolism of Fenbendazole. Fenbendazole D3 is a broad-spectrum anthelmintic drug that is commonly used to treat a variety of parasitic infections in animals. It is highly effective against nematode, cestode, and trematode parasites.
Fenbendazole D3 works by inhibiting the polymerization of tubulin, which leads to the disruption of microtubule formation and ultimately results in the death of the parasite. It is well absorbed from the gastrointestinal tract and extensively metabolized in the liver, with the major metabolites being fenbendazole sulfone and fenbendazole sulfide. These metabolites are excreted mainly in the urine and feces.
Fenbendazole D3 is used in research studies to investigate the PK and metabolism of Fenbendazole in different animal models. It is also used as an internal standard in mass spectrometry-based assays for the quantification of Fenbendazole and its metabolites in biological samples. The use of Fenbendazole D3 in such studies allows for accurate and precise measurements of Fenbendazole and its metabolites in biological matrices. In conclusion, Fenbendazole D3 is a useful tool for researchers studying the pharmacokinetics and metabolism of Fenbendazole, and it has important applications in the development of new anthelmintic drugs.