CAS No.
[957-56-2 (Unlabeled)]
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Previscan-d4; 2-(4-fluorophenyl)-1H-indene-1,3(2H)-dione-4,5,6,7-d4
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Fluindione-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Fluindione-d4 usage and description
Fluindione D4 is a stable isotope labelled derivative of Fluindione, an anticoagulant drug used in the prevention and treatment of blood clots. As a vitamin K antagonist, Fluindione D4 works by inhibiting the production of clotting factors in the liver, thereby slowing down the clotting process and reducing the risk of thrombosis.
Fluindione D4 is primarily used in pharmacokinetic studies and clinical trials to monitor the absorption, distribution, metabolism, and excretion of Fluindione in the body. By using Fluindione D4 as a tracer molecule, researchers can accurately measure the pharmacokinetic parameters of Fluindione in human or animal subjects, which can provide valuable insights into its efficacy and safety.
Chemically, Fluindione D4 is a deuterated analogue of Fluindione, with four deuterium atoms substituted for four hydrogen atoms in its molecular structure. The incorporation of deuterium atoms enhances the stability and specificity of Fluindione D4, making it an ideal compound for use in pharmacokinetic studies.
Fluindione D4 is available in the form of a white crystalline powder, which can be dissolved in organic solvents such as methanol or acetonitrile. It should be handled with care as it is a potentially hazardous material and may cause skin, eye, or respiratory irritation if not handled properly.
In summary, Fluindione D4 is a valuable tool for researchers and clinicians studying the pharmacokinetics of Fluindione. Its stable isotope labelling and chemical properties make it a safe and effective tracer molecule for use in clinical trials and pharmacological studies.
