Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Nifedipine-d6, 1188266-14-9
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 95 %
Hazard Compound
No -Refer MSDS for accurate information
Nifedipine-d6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Nifedipine-d6 usage and description
Nifedipine D6 is a deuterated analog of the calcium channel blocker nifedipine that is commonly used for the treatment of hypertension, angina, and other cardiovascular conditions. This compound has the same molecular formula as nifedipine (C17H18N2O6), but with six of its hydrogen atoms replaced by deuterium atoms.
Nifedipine D6 works by blocking the influx of calcium ions into vascular smooth muscle cells and cardiac cells, leading to vasodilation and reduced cardiac contractility. This results in decreased blood pressure and improved blood flow to the heart.
The deuterium substitution in Nifedipine D6 allows for its incorporation into metabolic studies and pharmacokinetic studies, as it can be easily distinguished from the non-deuterated compound in mass spectrometry analyses.
Nifedipine D6 is typically administered orally in the form of extended-release tablets, with a typical daily dose ranging from 20-60 mg. It is important to note that this compound should not be used in patients with hypotension, aortic stenosis, or acute myocardial infarction. Common side effects of Nifedipine D6 include headache, dizziness, flushing, and peripheral edema.
Overall, Nifedipine D6 is a useful tool in cardiovascular research and provides valuable insights into the pharmacokinetics and metabolism of nifedipine.
