Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
3-Methyl 5-(2-(methyl-d3)propyl-3,3,3-d3) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Nisoldipine-d6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
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material handover.
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Nisoldipine-d6 usage and description
Nisoldipine D6 is a deuterated form of the calcium channel blocker, Nisoldipine, which is used to treat high blood pressure. Deuterium is a stable isotope of hydrogen, and the incorporation of deuterium into the molecule can confer certain advantages such as increased stability and improved pharmacokinetics.
Nisoldipine D6 works by blocking the influx of calcium ions into the smooth muscle cells of the blood vessels, which results in relaxation and dilation of the vessels. This reduces the resistance to blood flow, thereby lowering blood pressure. Nisoldipine D6 is a dihydropyridine-type calcium channel blocker, which means it selectively targets the L-type calcium channels found in the smooth muscle cells of the cardiovascular system.
The chemical formula of Nisoldipine D6 is C20H18D6N2O6, and its molecular weight is 422.49 g/mol. It is a white to off-white crystalline powder that is sparingly soluble in water and soluble in organic solvents. Nisoldipine D6 is typically administered orally in the form of tablets or capsules.
Like other calcium channel blockers, Nisoldipine D6 can cause certain side effects such as dizziness, headache, flushing, and ankle swelling. It is important to follow the dosage instructions provided by a healthcare provider and to report any adverse effects experienced while taking the medication.
