Therapeutic Uses
Anti-Asthma / COPD
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Roflumilast N-Oxide-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Roflumilast N-Oxide-d4 usage and description
Roflumilast N-oxide D4 is a deuterated analogue of Roflumilast N-oxide, a potent and selective inhibitor of phosphodiesterase 4 (PDE4), which is involved in the regulation of inflammatory responses. This compound is commonly used in research to investigate the effects of PDE4 inhibition on various biological processes, particularly in the context of respiratory diseases such as chronic obstructive pulmonary disease (COPD).
Chemically, Roflumilast N-oxide D4 is a deuterated derivative of Roflumilast N-oxide, which means that some of the hydrogen atoms in the molecule have been replaced with deuterium atoms, a stable isotope of hydrogen. This modification is often used in drug development and research to improve the pharmacokinetic properties of a compound, such as its bioavailability and metabolic stability.
In terms of usage, Roflumilast N-oxide D4 is typically administered to cells or animals in vitro or in vivo to study its effects on PDE4 activity and related biological processes. Studies have shown that PDE4 inhibition can reduce inflammation, airway hyperresponsiveness, and mucus production in animal models of respiratory diseases, suggesting that it may be a promising therapeutic target for these conditions.
Overall, Roflumilast N-oxide D4 is a valuable tool for researchers studying PDE4 inhibition and its potential therapeutic applications in respiratory diseases.
