Therapeutic Uses
Antibiotics
Synonyms
Didechloro Vancomycin B
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Vancomycin Didechloro Impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Vancomycin Didechloro Impurity usage and description
Vancomycin is a glycopeptide antibiotic that is commonly used to treat severe bacterial infections such as methicillin-resistant Staphylococcus aureus (MRSA). However, during the manufacturing process of vancomycin, it is possible for impurities to be introduced into the final product. One of these impurities is vancomycin didechloro impurity.
Vancomycin didechloro impurity is a degradation product of vancomycin that is formed when two chlorine atoms are removed from the molecule. This impurity is a potential concern because it may decrease the effectiveness of the antibiotic and also cause adverse effects in patients. Therefore, it is important to monitor the presence of vancomycin didechloro impurity in vancomycin products.
Analytical methods such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) can be used to detect and quantify vancomycin didechloro impurity. The acceptable limit for vancomycin didechloro impurity in vancomycin products is typically set at 0.2% or lower.
In conclusion, vancomycin didechloro impurity is a degradation product of vancomycin that can potentially affect the efficacy and safety of the antibiotic. Therefore, its presence in vancomycin products should be monitored and controlled to ensure the quality of the medication.
