Therapeutic Uses
Anti-Migraines
Storage Condition
Store at freezer (-20ยฐC) for long term storage
Synonyms
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-(2-Methoxyethyl) 5-(1-Methylethyl-d7) Ester
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 95 %
Hazard Compound
No -Refer MSDS for accurate information
Nimodipine-d7 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Nimodipine-d7 usage and description
Nimodipine D7 is a deuterated analog of the calcium channel blocker Nimodipine. It is used in the treatment of cerebral vasospasm, a condition in which the blood vessels in the brain narrow and restrict blood flow, typically occurring after a subarachnoid hemorrhage. Nimodipine D7 works by relaxing the smooth muscles in the walls of the blood vessels, thereby increasing blood flow to the brain.
The chemical formula of Nimodipine D7 is C21H22D7N2O7, and its molecular weight is 428.56 g/mol. It is a yellow crystalline powder that is practically insoluble in water and soluble in organic solvents such as ethanol and methanol.
Nimodipine D7 is typically administered orally in the form of capsules, with a recommended dosage of 60mg every 4 hours for 21 consecutive days. It is important to follow the prescribed dosage and duration of treatment, as overdose or sudden discontinuation can lead to adverse effects such as hypotension and rebound vasospasm.
Nimodipine D7 is metabolized in the liver, with its primary metabolite being Nimodipine glucuronide. It is primarily eliminated through urine, with a half-life of approximately 8 hours in healthy individuals.
In conclusion, Nimodipine D7 is an important medication used in the treatment of cerebral vasospasm. Its mechanism of action, chemical properties and recommended usage should be carefully considered by healthcare professionals in order to ensure safe and effective treatment for patients.