Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
N-[4-Nitro-2-(D5)phenoxyphenyl]methanesulfonamide
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Nimesulide-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
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Nimesulide-d5 usage and description
Nimesulide D5 is a deuterated form of Nimesulide, a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is a selective cyclooxygenase-2 (COX-2) inhibitor, which means it specifically targets the enzyme responsible for inflammation and pain, without affecting the enzyme responsible for protecting the stomach lining.
Nimesulide D5 is used to treat a variety of conditions, including osteoarthritis, rheumatoid arthritis, and acute pain. It is also used to treat fever and pain associated with respiratory tract infections. The drug works by blocking the production of prostaglandins, which are responsible for inflammation and pain.
Chemically, Nimesulide D5 is a white to off-white crystalline powder, with a molecular weight of 314.39 g/mol. It is slightly soluble in water and ethanol, and has a melting point of 157-161ยฐC. The deuterated form of Nimesulide is used in pharmacokinetic studies, where the deuterium atoms are used as tracers to track the metabolism of the drug in the body.
Nimesulide D5 should be taken as directed by a healthcare professional, as it can cause side effects such as gastrointestinal bleeding, liver damage, and allergic reactions. It should not be taken by individuals with a history of ulcers, bleeding disorders, or liver disease. Overall, Nimesulide D5 is a useful medication for treating pain and inflammation, and has a specific mechanism of action that reduces the risk of gastrointestinal side effects compared to other NSAIDs.