Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Colchicine-D3 (N-acetyl-D3)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Colchicine-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Colchicine-d3 usage and description
Colchicine D3 is a deuterated form of colchicine, a naturally occurring compound found in the autumn crocus plant. This compound is commonly used as a medication for the treatment of gout and familial Mediterranean fever. It works by binding to tubulin, a protein critical for cell division, and inhibiting its polymerization, thus preventing the formation of microtubules. This leads to the suppression of neutrophil activity, which is responsible for the inflammation and pain associated with gout attacks.
Colchicine D3 is a stable isotope-labeled compound, which means that it contains three deuterium atoms instead of hydrogen atoms. This provides a useful tool for researchers to study the pharmacokinetics and metabolism of colchicine in vivo, as well as to verify the identity and purity of colchicine in analytical methods.
The chemical formula of Colchicine D3 is C22H25D3NO6, with a molecular weight of 419.50 g/mol. It is a white to off-white crystalline powder, soluble in methanol, ethanol, and dimethyl sulfoxide. The compound is stable under normal conditions but should be stored in a cool, dry place away from light and moisture.
In summary, Colchicine D3 is a valuable tool for research and a potent medication for the treatment of gout and familial Mediterranean fever. Its deuterated form provides an additional level of precision and accuracy in analytical methods and pharmacokinetic studies.
