Therapeutic Uses
Anti-Fungals
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difuorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one-D4
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Posaconazole-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
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While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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Posaconazole-d4 usage and description
Posaconazole D4 is a deuterated analog of posaconazole, which is a triazole antifungal agent used for the treatment of various fungal infections. The deuterium substitution in Posaconazole D4 provides a unique tool for pharmacokinetic and pharmacodynamic studies of posaconazole.
Posaconazole D4 is typically used in clinical studies as a stable isotope-labeled internal standard for the quantification of posaconazole in biological fluids and tissues. It is also used in research to investigate drug-drug interactions, metabolism, and pharmacokinetics of posaconazole.
The chemical formula of Posaconazole D4 is C37H41D4F2N5O4, and its molecular weight is 666.81 g/mol. It is a white to off-white powder with high purity and stability. The compound is soluble in organic solvents such as methanol, ethanol, and acetonitrile but insoluble in water.
Posaconazole D4 is synthesized through deuterium exchange reactions using labeled starting materials. The compound is then purified using chromatography techniques to obtain a high-quality product.
In conclusion, Posaconazole D4 is a valuable tool for pharmacokinetic and pharmacodynamic studies of posaconazole. Its unique properties allow for accurate quantification and investigation of the drug's metabolism and interactions, making it an essential component of research in antifungal therapy.
