Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
Acyclovir L-Isoleucinate
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Valaciclovir EP Impurity J is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Valaciclovir EP Impurity J usage and description
Acyclovir L-Isoleucinate is an antiviral drug that is used to treat infections caused by the herpes simplex virus and the varicella-zoster virus. The drug works by inhibiting the replication of the virus, thereby preventing the spread of the infection. Acyclovir L-Isoleucinate is a prodrug of Acyclovir, which means that it is converted into Acyclovir in the body. The L-Isoleucine moiety improves the solubility and stability of the drug, making it more effective and easier to administer.
The chemical formula of Acyclovir L-Isoleucinate is C20H34N5O6 and its molecular weight is 454.52 g/mol. The drug is administered intravenously and is rapidly converted into Acyclovir in the plasma. The half-life of Acyclovir L-Isoleucinate is approximately 2 hours, while the half-life of Acyclovir is approximately 3 hours. The drug is eliminated from the body primarily through the kidneys, with approximately 84% of the dose excreted unchanged.
Acyclovir L-Isoleucinate is generally well-tolerated, with the most common side effects being nausea, vomiting, and diarrhea. The drug is contraindicated in patients with a known hypersensitivity to Acyclovir or any of its components. It should be used with caution in patients with renal impairment, as the drug is primarily excreted through the kidneys. Overall, Acyclovir L-Isoleucinate is an effective antiviral drug that is widely used in the treatment of herpes simplex virus and varicella-zoster virus infections.