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Impurity Product Detail
Home Impurity Sofosbuvir CS-O-11148

Sofosbuvir Dimer

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Product Code: CS-O-11148 Impurity Research Use Only
Sofosbuvir Dimer
Category
Impurity
API Family
Sofosbuvir
Product Code
CS-O-11148
Research Status
For Laboratory Use

Sofosbuvir Dimer

Sofosbuvir Impurity
Stock Status: In Stock
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CAT No.
CS-O-11148
CAS No.
1256490-29-5
Molecular Formula
C34H45FN4O13P2
Molecular Weight
798.69
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
1256490-29-5
Product Code
CS-O-11148
M.F.
C34H45FN4O13P2
M.W.
798.69
Smiles
CC(C)OC([C@H](C)NP(O[C@@H]1[C@H](O[C@@H](N2C(NC(C=C2)=O)=O)[C@@]1(F)C)COP(OC3=CC=CC=C3)(N[C@@H](C)C(OC(C)C)=O)=O)(OC4=CC=CC=C4)=O)=O
Category
Impurity
API Family
Sofosbuvir
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(2S)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate
References
"Lam, A,M,,et al,: Antimicrob, Agents, Chemotherapy,, 56, 3359 (2012); Lam, A,M,, et al,: J, Virol,, 85, 12334 (2011); Sofia, M,J,, et al,: J, Medn, Chem,, 53, 7202 (2010)"
Synonyms
(2S)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate
Application Notes
"Sofosbuvir 3’,5’-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-a-fluoro-ß-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treat"
Purity by HPLC
93.44%
Hazard Compound
Refer MSDS for accurate information.
Overview
"Sofosbuvir 3’,5’-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-a-fluoro-ß-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treat"

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