Clarithromycin EP impurity O

127252-80-6

CS-O-11827

C₃₉H₇₂N₂O₁₃

776.99

CO[C@](C)(C[C@H](/C([C@@H]([C@H]([C@](O)([C@H](OC([C@@H]([C@H]([C@@H]1C)O[C@H]2C[C@](C)([C@H]([C@@H](O2)C)O)OC)C)=O)CC)C)O)C)=N/OC)C)[C@@H]1O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O

Impurity

Clarithromycin

Store at refrigerator (2-8°C) for long term storage

(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-10-(methoxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

"Morgan; D,; et al,: J, Chromatogr,; 502; 351 (1990); Benson; C,; et al,: Eur, J, Clin, Microbiol,; 6; 173 (1987); Boyanova; L,; et al,: J, Med, Microb,; 61; 85 (2012); Lin; Z,; et al,: Toxicol, Sci,; 126; 114 (2012)"

Clarithromycin EP impurity O;6-O-Methylerythromycin (9Z)-9-O-Methyloxime;(3R;4S;5S;6R;7R;9R;10Z;11S;12R;13S;14R)-6- {[(2S;3R;4S;6R)-4-(dimethylamino)-3-hydroxy-6- methyloxan-2-yl]oxy}-14-ethyl-12;13-dihydroxy-4- {[(2R;4R;5S;6S)-5-hydroxy-4-methoxy-4;6- dimethyloxan-2-yl]oxy}-7-methoxy-10-(methoxyimino)- 3;5;7;9;11;13-hexamethyl-1-oxacyclotetradecan-2- one

Impurity in commercial preparations of Clarithromycin.

Not less than 90%

Refer MSDS for accurate information.