Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Carbamic acid, [3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, phenylmethyl ester, [R-(R*,S*)]- (ZCI)
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Darunavir СВZ amino impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
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basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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Darunavir СВZ amino impurity usage and description
Darunavir is a drug used to treat human immunodeficiency virus (HIV) infections. It works by inhibiting the activity of the viral protease enzyme, which is essential for the virus to replicate and mature. Darunavir is available in various formulations, including tablets, oral suspension, and extended-release tablets. However, during the manufacturing process, impurities may be introduced into the drug substance. One such impurity is the Darunavir СВZ amino impurity.
The Darunavir СВZ amino impurity is a chemical byproduct that occurs during the synthesis of Darunavir. It is a small molecule that contains an amino group and a carboxyl group. This impurity is considered to be a potential genotoxic and mutagenic agent, and therefore, its presence in Darunavir needs to be controlled.
The maximum allowable level of the Darunavir СВZ amino impurity in Darunavir drug substance is 0.15%. The impurity can be removed by various purification techniques, including chromatography, crystallization, and recrystallization.
In conclusion, the Darunavir СВZ amino impurity is a chemical byproduct that can be present in Darunavir drug substance. Its presence needs to be controlled due to its potential genotoxic and mutagenic properties. Various purification techniques can be used to remove this impurity and ensure the safety and efficacy of Darunavir.
