CAS No.
[33419-42-0(Unlabeled)]
Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Etoposide-d3, 33419-42-0(Unlabeled)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Etoposide-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Etoposide-d3 usage and description
Etoposide D3 is a deuterium-labeled derivative of etoposide, a type of chemotherapy drug that is commonly used to treat different types of cancers including testicular, lung, ovarian, and lymphoma. Etoposide D3 is used in clinical research studies to investigate the pharmacokinetics, pharmacodynamics, and metabolism of etoposide in humans.
Etoposide D3 works by inhibiting the activity of an enzyme called topoisomerase II, which is responsible for unwinding and re-joining the DNA strands during cell replication. By inhibiting this enzyme, etoposide D3 prevents the replication of cancer cells, thereby slowing down or stopping their growth.
Chemically, etoposide D3 is a semi-synthetic derivative of podophyllotoxin, a natural product found in the Mayapple plant. It has a molecular formula of C29H37D3NO13 and a molecular weight of 609.7 g/mol. Etoposide D3 is administered intravenously and is usually given in combination with other chemotherapy drugs or radiation therapy.
While etoposide D3 is generally well-tolerated, it can cause side effects such as nausea, vomiting, hair loss, fatigue, and an increased risk of infection. Patients receiving etoposide D3 should be closely monitored for any adverse effects and adjustments to the dosage may be necessary depending on the patient's individual response to the drug. Overall, etoposide D3 is an important tool in cancer research and treatment, helping to improve our understanding of the mechanisms underlying cancer and develop more effective therapies for patients.
