Therapeutic Uses
Anti-Hyperlipidemics
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
calcium (3R,5R)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyheptanoate
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
6,7-Dihydro Rosuvastatin Calcium is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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6,7-Dihydro Rosuvastatin Calcium usage and description
6,7-Dihydro Rosuvastatin Calcium is a chemical compound that belongs to the statin class of drugs. It is an active pharmaceutical ingredient found in various medications used to treat high cholesterol, including Rosuvastatin. Rosuvastatin is a potent inhibitor of HMG-CoA reductase, an enzyme that plays a crucial role in the synthesis of cholesterol in the liver. As a result, it helps to lower levels of low-density lipoprotein (LDL) cholesterol, also known as "bad" cholesterol, in the blood.
The chemical structure of 6,7-Dihydro Rosuvastatin Calcium is composed of a pyrimidine ring, a lactone ring, and a side chain with a carboxylic acid group. It is a white to off-white crystalline powder that is soluble in water, methanol, and ethanol. The molecular formula of 6,7-Dihydro Rosuvastatin Calcium is C44H54CaF2N6O12S2, and its molecular weight is 1001.14 g/mol.
When used as a medication, 6,7-Dihydro Rosuvastatin Calcium is usually administered orally as a tablet. Its pharmacokinetics are well characterized, with a bioavailability of around 20% and a half-life of approximately 19 hours. The drug is primarily eliminated through the feces, with only a small amount excreted in the urine.
In conclusion, 6,7-Dihydro Rosuvastatin Calcium is an important pharmaceutical ingredient that helps to lower cholesterol levels in individuals with high cholesterol. Its chemical structure and pharmacokinetics have been extensively studied, making it a safe and effective medication for the treatment of hypercholesterolemia.